Neuroleptic malignant syndrome

What is neuroleptic malignant syndrome?
Neuroleptic malignant syndrome is a rare life-threatening neurological disorder most often caused by neuroleptic or antipsychotic drugs. Symptoms usually involve muscle rigidity, high fever, unstable blood pressure, and changes in cognition that can lead to delirium, and coma. Creatine kinase levels are elevated, which helps in making the diagnosis.

---
New England Journal of Medicine - Vol. 359, No. 8, August 21, 2008