Q: What conditions could cause waxing and waning pulmonary nodules?
A: Waxing and waning pulmonary nodules can occur with several conditions. Sarcoidosis is one possible diagnosis in a patient who also has hilar and mediastinal adenopathy. Patients with rheumatoid arthritis can also have cavitary nodules that relapse and remit in concert with systemic disease activity. Other conditions to consider include Wegener's granulomatosis and chronic thromboembolic disease.
Teaching topics from the New England Journal of Medicine - Vol. 358, No. 6, February 7, 2008