2009年12月8日 星期二

Transtubular potassium gradient (TTKG)


Indications:Hyperkalemia

Precautions:
  • Results altered by Hyperkalemia Management.
  • Obtain lab sample prior to intervention if possible.
  • Do not delay treatment in emergent Hyperkalemia.
Labs:
  • Serum Potassium and Serum Osmolality.
  • Spot urine for Urine Potassium and Urine Osmolality.
Formula of Transtubular Potassium Gradient (TTPG):
  • TTPG = (Urine K+ x Serum Osm)/(Serum K+ x Urine Osm)
    ... where K+ is potassium and Osm is Osmolality.
Interpretation of Fractional Excretion of Potassium:
  • TTPG <6-8%:>
  • TTPG). TTPG >6-8: Extrarenal cause of Hyperkalemia (May also be increased in Chronic Renal Failure).

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