TPA for stroke 可延長至 4.5 小時

Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III).

Conclusion:
Our results support the use of alteplase up to 4.5 h after the onset of stroke symptoms across a broad range of subgroups of patients who meet the requirements of the European product label but miss the approved treatment window of 0-3 h.

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Lancet Neurol. 2009 Oct 20.
http://linkinghub.elsevier.com/retrieve/pii/S1474-4422(09)70264-9