Name five physiologic factors (i.e. not genetic disorders) that predispose a patient to a premature weakening of the aortic wall resulting in a greater incidence of aortic dissection at a younger age.
1. Bicuspid aortic valve,
2. dilated aortic valve,
3. coarctation of the aorta,
4. pregnancy, and
5. transient profound elevations of blood pressure (e.g. cocaine abuse, weight lifting, Beta-blocker withdrawal)
Reference: Journal of EM, April, 2005, pg. 287