Young aortic dissection

Question:
Name five physiologic factors (i.e. not genetic disorders) that predispose a patient to a premature weakening of the aortic wall resulting in a greater incidence of aortic dissection at a younger age.

Answer:
1. Bicuspid aortic valve,
2. dilated aortic valve,
3. coarctation of the aorta,
4. pregnancy, and
5. transient profound elevations of blood pressure (e.g. cocaine abuse, weight lifting, Beta-blocker withdrawal)

Reference: Journal of EM, April, 2005, pg. 287